Mantle-Cell Lymphomas
《英文msh詞典》Mantle-Cell Lymphomas
[入口詞] Mantle-Cell Lymphomas
[主題詞] Lymphoma,Mantle-Cell
[英文釋義] A rare form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the cyclin D1 gene (GENES,BCL-1).